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Brucellosis

ORPHA:1304 · Disease · Disorder

HPO 表現型（共 77 項）

Very frequent (99-80%)(1)

  • Abnormality of the liverHP:0001392

Frequent (79-30%)(19)

  • Abnormal hepatobiliary system physiologyHP:0025155
  • Abnormality of the gastrointestinal tractHP:0011024
  • AnemiaHP:0001903
  • AnorexiaHP:0002039
  • ArthralgiaHP:0002829
  • ArthritisHP:0001369
  • AstheniaHP:0025406
  • Decreased total leukocyte countHP:0001882
  • Elevated circulating C-reactive protein concentrationHP:0011227
  • Elevated erythrocyte sedimentation rateHP:0003565
  • FatigueHP:0012378
  • FeverHP:0001945
  • HepatomegalyHP:0002240
  • HyperhidrosisHP:0000975
  • Increased circulating IgG concentrationHP:0003237
  • NauseaHP:0002018
  • Septic arthritisHP:0003095
  • SplenomegalyHP:0001744
  • Weight lossHP:0001824

Occasional (29-5%)(39)

  • Abdominal painHP:0002027
  • Abnormal bone marrow cell morphologyHP:0005561
  • Abnormal respiratory system morphologyHP:0012252
  • Abnormality of the genitourinary systemHP:0000119
  • Abnormality of the nervous systemHP:0000707
  • Abnormality of the peripheral nervous systemHP:0410008
  • Abnormality of the skinHP:0000951
  • BronchitisHP:0012387
  • ChillsHP:0025143
  • Cutaneous cystHP:0025245
  • DepressionHP:0000716
  • EpididymitisHP:0000031
  • Erythematous papuleHP:0030350
  • Failure to thriveHP:0001508
  • GlomerulonephritisHP:0000099
  • GranulomaHP:0032252
  • HeadacheHP:0002315
  • Hip osteoarthritisHP:0008843
  • HypersplenismHP:0001971
  • Immunologic hypersensitivityHP:0100326
  • Increased circulating IgM concentrationHP:0003496
  • Increased total leukocyte countHP:0001974
  • Knee osteoarthritisHP:0005086
  • Liver abscessHP:0100523
  • LymphadenopathyHP:0002716
  • Morphological central nervous system abnormalityHP:0002011
  • OrchitisHP:0100796
  • OsteomyelitisHP:0002754
  • Peripheral neuropathyHP:0009830
  • Pleural effusionHP:0002202
  • PneumoniaHP:0002090
  • Premature birthHP:0001622
  • PurpuraHP:0000979
  • Rheumatoid factor positiveHP:0002923
  • Sacroiliac arthritisHP:0012317
  • Small for gestational ageHP:0001518
  • Spontaneous abortionHP:0005268
  • ThrombocytopeniaHP:0001873
  • VomitingHP:0002013

Very rare (<4-1%)(18)

  • Abnormal aortic valve morphologyHP:0001646
  • Abnormal cranial nerve physiologyHP:0031910
  • Abnormality of the cardiovascular systemHP:0001626
  • Anterior uveitisHP:0012122
  • ArteritisHP:0012089
  • Atypical behaviorHP:0000708
  • ChoreaHP:0002072
  • ChorioretinitisHP:0012424
  • EndocarditisHP:0100584
  • Infectious encephalitisHP:0002383
  • Intrarenal abscessHP:0032620
  • Lung abscessHP:0025044
  • MyocarditisHP:0012819
  • PericarditisHP:0001701
  • Pulmonary granulomatosisHP:0030250
  • ThrombocytosisHP:0001894
  • ThrombophlebitisHP:0004418
  • Transient ischemic attackHP:0002326