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Subacute inflammatory demyelinating polyneuropathy

ORPHA:206594 · Disease · Disorder

HPO 表現型（共 40 項）

Very frequent (99-80%)(5)

  • Abnormality of somatosensory evoked potentialsHP:0007377
  • Decreased motor nerve conduction velocityHP:0003431
  • Decreased nerve conduction velocityHP:0000762
  • Increased CSF protein concentrationHP:0002922
  • Muscle weaknessHP:0001324

Frequent (79-30%)(16)

  • AreflexiaHP:0001284
  • Axonal lossHP:0003447
  • Decreased amplitude of sensory action potentialsHP:0007078
  • Demyelinating motor neuropathyHP:0007220
  • Difficulty climbing stairsHP:0003551
  • Diffuse peripheral demyelinationHP:0006881
  • Elevated erythrocyte sedimentation rateHP:0003565
  • Frequent fallsHP:0002359
  • Functional motor deficitHP:0004302
  • Gait disturbanceHP:0001288
  • Increased total leukocyte countHP:0001974
  • PainHP:0012531
  • Peripheral demyelinationHP:0011096
  • Sensorimotor neuropathyHP:0007141
  • Somatic sensory dysfunctionHP:0003474
  • Symmetric peripheral demyelinationHP:0007262

Occasional (29-5%)(16)

  • Abnormal calf musculature morphologyHP:0001430
  • Absent patellar reflexesHP:0006844
  • ChoreoathetosisHP:0001266
  • Decreased distal sensory nerve action potentialHP:0007230
  • Decreased sensory nerve conduction velocityHP:0003448
  • Distal muscle weaknessHP:0002460
  • Distal sensory impairmentHP:0002936
  • Increased circulating IgG concentrationHP:0003237
  • Limitation of movement at anklesHP:0010505
  • Limited elbow flexionHP:0006376
  • Limited hip movementHP:0008800
  • Motor conduction blockHP:0012078
  • Positive Romberg signHP:0002403
  • Severe infectionHP:0032169
  • Steppage gaitHP:0003376
  • TremorHP:0001337

Very rare (<4-1%)(3)

  • Abnormality of the autonomic nervous systemHP:0002270
  • Abnormality of the respiratory systemHP:0002086
  • Cranial nerve paralysisHP:0006824