← 返回搜尋

Progressive supranuclear palsy-progressive non-fluent aphasia syndrome

ORPHA:240112 · Clinical subtype · Subtype of disorder

HPO 表現型（共 21 項）

Very frequent (99-80%)(7)

  • Abnormal speech patternHP:0002167
  • Anomic aphasiaHP:0030784
  • Deficit in grammarHP:0006977
  • Deficit in phonologic short-term memoryHP:0002549
  • Speech apraxiaHP:0011098
  • Spoken word recognition deficitHP:0030391
  • StutteringHP:0025268

Frequent (79-30%)(5)

  • Abnormal prosodyHP:0031434
  • ApathyHP:0000741
  • Mental deteriorationHP:0001268
  • Poor speechHP:0002465
  • Speech articulation difficultiesHP:0009088

Occasional (29-5%)(9)

  • AphasiaHP:0002381
  • ClumsinessHP:0002312
  • DysphagiaHP:0002015
  • FallsHP:0002527
  • Limb apraxiaHP:0030217
  • ParkinsonismHP:0001300
  • Postural instabilityHP:0002172
  • Progressive extrapyramidal muscular rigidityHP:0007158
  • Vertical supranuclear gaze palsyHP:0000511