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HELLP syndrome

ORPHA:244242 · Disease · Disorder

HPO 表現型（共 32 項）

Obligate (100%)(2)

  • Elevated circulating hepatic transaminase concentrationHP:0002910
  • ThrombocytopeniaHP:0001873

Very frequent (99-80%)(1)

  • Hemolytic anemiaHP:0001878

Frequent (79-30%)(9)

  • FatigueHP:0012378
  • Generalized edemaHP:0007430
  • HeadacheHP:0002315
  • HypofibrinogenemiaHP:0011900
  • Increased body weightHP:0004324
  • Maternal hypertensionHP:0008071
  • PreeclampsiaHP:0100602
  • Prolonged prothrombin timeHP:0008151
  • ProteinuriaHP:0000093

Occasional (29-5%)(17)

  • Abdominal painHP:0002027
  • Back painHP:0003418
  • Decreased mean corpuscular hemoglobin concentrationHP:0025547
  • Disseminated intravascular coagulationHP:0005521
  • EclampsiaHP:0100601
  • Epigastric painHP:0410019
  • HemoglobinuriaHP:0003641
  • HypotensionHP:0002615
  • Increased circulating lactate dehydrogenase concentrationHP:0025435
  • Microangiopathic hemolytic anemiaHP:0001937
  • NauseaHP:0002018
  • Placental abruptionHP:0011419
  • Pleural effusionHP:0002202
  • Poor wound healingHP:0001058
  • Pulmonary edemaHP:0100598
  • Shoulder painHP:0030834
  • VomitingHP:0002013

Very rare (<4-1%)(3)

  • Acute kidney injuryHP:0001919
  • Cerebral hemorrhageHP:0001342
  • Internal hemorrhageHP:0011029