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Generalized pustular psoriasis

ORPHA:247353 · Disease · Disorder

HPO 表現型（共 27 項）

Obligate (100%)(4)

  • ArthralgiaHP:0002829
  • Elevated erythrocyte sedimentation rateHP:0003565
  • Erythematous plaqueHP:0025474
  • PustuleHP:0200039

Very frequent (99-80%)(3)

  • Abnormal nail morphologyHP:0001597
  • ErythrodermaHP:0001019
  • PainHP:0012531

Frequent (79-30%)(8)

  • ArthritisHP:0001369
  • CheilitisHP:0100825
  • Elevated circulating C-reactive protein concentrationHP:0011227
  • FatigueHP:0012378
  • FeverHP:0001945
  • Geographic tongueHP:0025252
  • Increased total leukocyte countHP:0001974
  • OverweightHP:0025502

Occasional (29-5%)(9)

  • Decreased total lymphocyte countHP:0001888
  • Elevated circulating hepatic transaminase concentrationHP:0002910
  • HypoalbuminemiaHP:0003073
  • HypocalcemiaHP:0002901
  • HyponatremiaHP:0002902
  • ObesityHP:0001513
  • Palmoplantar pustulosisHP:0100847
  • Pedal edemaHP:0010741
  • Renal insufficiencyHP:0000083

Very rare (<4-1%)(3)

  • Congestive heart failureHP:0001635
  • SepsisHP:0100806
  • UveitisHP:0000554