← 返回搜尋

Meningioma

ORPHA:2495 · Disease · Disorder

HPO 表現型（共 74 項）

Very frequent (99-80%)(3)

  • Chromosomal breakage induced by ionizing radiationHP:0010997
  • Increased sensitivity to ionizing radiationHP:0011133
  • Intracranial meningiomaHP:0100009

Frequent (79-30%)(19)

  • Abnormal brain FDG positron emission tomographyHP:0012658
  • AmenorrheaHP:0000141
  • Bitemporal hemianopiaHP:0030521
  • Decreased circulating ACTH concentrationHP:0002920
  • Decreased circulating cortisol levelHP:0008163
  • Decreased circulating follicle stimulating hormone concentrationHP:0030341
  • Decreased circulating luteinizing hormone levelHP:0030344
  • Decreased serum estradiolHP:0008214
  • Decreased serum testosterone concentrationHP:0040171
  • Focal T2 hypointense thalamic lesionHP:0012691
  • Focal-onset seizureHP:0007359
  • HeadacheHP:0002315
  • Hypogonadotropic hypogonadismHP:0000044
  • ImpotenceHP:0000802
  • Increased circulating prolactin concentrationHP:0000870
  • Nausea and vomitingHP:0002017
  • Pituitary hypothyroidismHP:0008245
  • Secondary growth hormone deficiencyHP:0008240
  • SeizureHP:0001250

Occasional (29-5%)(32)

  • Abnormal central motor functionHP:0011442
  • Abnormal central sensory functionHP:0011730
  • Abnormal cerebellum morphologyHP:0001317
  • Abnormal hypothalamus physiologyHP:0012285
  • Abnormal kinetic perimetry testHP:0030591
  • Abnormality of the sense of smellHP:0004408
  • AtaxiaHP:0001251
  • Cognitive impairmentHP:0100543
  • Cranial nerve paralysisHP:0006824
  • Enlarged pituitary glandHP:0012505
  • Facial palsyHP:0010628
  • Functional motor deficitHP:0004302
  • Gait disturbanceHP:0001288
  • HemiparesisHP:0001269
  • HydrocephalusHP:0000238
  • Hypothalamic hypothyroidismHP:0008237
  • Increased intracranial pressureHP:0002516
  • Lower limb muscle weaknessHP:0007340
  • Memory impairmentHP:0002354
  • Neoplasm of the anterior pituitaryHP:0011750
  • NeurofibromaHP:0001067
  • ObesityHP:0001513
  • Oculomotor nerve palsyHP:0012246
  • OphthalmoplegiaHP:0000602
  • PapilledemaHP:0001085
  • Reduced circulating prolactin concentrationHP:0008202
  • Slow decrease in visual acuityHP:0007924
  • Spinal meningiomaHP:0100010
  • Trigeminal neuralgiaHP:0100661
  • Upper limb muscle weaknessHP:0003484
  • Visual acuity test abnormalityHP:0030532
  • Weak extraocular musclesHP:0007715

Very rare (<4-1%)(20)

  • Abnormal mediastinum morphologyHP:0045026
  • Abnormal speech patternHP:0002167
  • Abnormality on pulmonary function testingHP:0030878
  • Back painHP:0003418
  • BlindnessHP:0000618
  • Brain stem compressionHP:0002512
  • Cerebral hemorrhageHP:0001342
  • Ear painHP:0030766
  • Emotional labilityHP:0000712
  • Excessive daytime somnolenceHP:0001262
  • Hemifacial spasmHP:0010828
  • Neoplasm of the posterior pituitaryHP:0011752
  • Neoplasm of the skinHP:0008069
  • Neoplasm of the tongueHP:0100648
  • Progressive pulmonary function impairmentHP:0006520
  • ProptosisHP:0000520
  • SyncopeHP:0001279
  • TinnitusHP:0000360
  • Transient global amnesiaHP:0010534
  • Urinary incontinenceHP:0000020