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Tick-borne encephalitis

ORPHA:297 · Disease · Disorder

HPO 表現型（共 63 項）

Very frequent (99-80%)(1)

  • CSF pleocytosisHP:0012229

Frequent (79-30%)(9)

  • Abnormal circulating cytokine concentrationHP:0011112
  • AnorexiaHP:0002039
  • ArthralgiaHP:0002829
  • Decreased total leukocyte countHP:0001882
  • FatigueHP:0012378
  • HeadacheHP:0002315
  • MyalgiaHP:0003326
  • NauseaHP:0002018
  • ViremiaHP:0020071

Occasional (29-5%)(40)

  • Abnormal autonomic nervous system physiologyHP:0012332
  • Abnormal cranial nerve morphologyHP:0001291
  • Abnormal glossopharyngeal nerve morphologyHP:3000047
  • Abnormality of the vestibular nerveHP:0011392
  • Atypical behaviorHP:0000708
  • Back painHP:0003418
  • Cognitive impairmentHP:0100543
  • Decreased vigilanceHP:0032044
  • DepressionHP:0000716
  • Diminished ability to concentrateHP:0031987
  • DysphagiaHP:0002015
  • Elevated circulating C-reactive protein concentrationHP:0011227
  • Elevated erythrocyte sedimentation rateHP:0003565
  • Excessive daytime somnolenceHP:0001262
  • Hearing impairmentHP:0000365
  • Hyperkinetic movementsHP:0002487
  • IncoordinationHP:0002311
  • Increased circulating IgG concentrationHP:0003237
  • Increased circulating IgM concentrationHP:0003496
  • Increased total leukocyte countHP:0001974
  • Limb painHP:0009763
  • MeningitisHP:0001287
  • OphthalmoplegiaHP:0000602
  • ParalysisHP:0003470
  • Personality changesHP:0000751
  • PhotophobiaHP:0000613
  • Reduced consciousnessHP:0004372
  • Skeletal muscle atrophyHP:0003202
  • Sleep disturbanceHP:0002360
  • Somatic sensory dysfunctionHP:0003474
  • Speech apraxiaHP:0011098
  • Stiff neckHP:0025258
  • ThrombocytopeniaHP:0001873
  • TinnitusHP:0000360
  • Tongue fasciculationsHP:0001308
  • TremorHP:0001337
  • Unusual CNS infectionHP:0011450
  • VertigoHP:0002321
  • Visual impairmentHP:0000505
  • VomitingHP:0002013

Very rare (<4-1%)(13)

  • Abnormal brainstem MRI signal intensityHP:0012747
  • Abnormal medulla oblongata morphologyHP:0011441
  • Abnormal myocardium morphologyHP:0001637
  • ComaHP:0001259
  • DeliriumHP:0031258
  • Elevated circulating hepatic transaminase concentrationHP:0002910
  • Facial palsyHP:0010628
  • Fatigable weakness of respiratory musclesHP:0030196
  • Focal-onset seizureHP:0007359
  • Generalized-onset seizureHP:0002197
  • MyelitisHP:0012486
  • PolyneuritisHP:0031003
  • PsychosisHP:0000709