← 返回搜尋

Langerhans cell histiocytosis

ORPHA:389 · Disease · Disorder

HPO 表現型（共 27 項）

Very frequent (99-80%)(2)

  • Bone painHP:0002653
  • OsteolysisHP:0002797

Frequent (79-30%)(7)

  • CoughHP:0012735
  • Eczematoid dermatitisHP:0000964
  • FeverHP:0001945
  • HepatomegalyHP:0002240
  • LymphadenopathyHP:0002716
  • Skin rashHP:0000988
  • SplenomegalyHP:0001744

Occasional (29-5%)(15)

  • AtaxiaHP:0001251
  • Decreased total leukocyte countHP:0001882
  • Diabetes insipidusHP:0000873
  • DysarthriaHP:0001260
  • Genital ulcersHP:0003249
  • Growth delayHP:0001510
  • Hearing impairmentHP:0000365
  • HypoalbuminemiaHP:0003073
  • Mental deteriorationHP:0001268
  • Oral ulcerHP:0000155
  • Pulmonary Langerhans cell histiocytosisHP:0034769
  • Reduced circulating growth hormone concentrationHP:0034323
  • Spontaneous pneumothoraxHP:0002108
  • ThrombocytopeniaHP:0001873
  • Weight lossHP:0001824

Very rare (<4-1%)(3)

  • Hepatic failureHP:0001399
  • Respiratory insufficiencyHP:0002093
  • Sclerosing cholangitisHP:0030991