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Graft versus host disease

ORPHA:39812 · Disease · Disorder

HPO 表現型（共 41 項）

Very frequent (99-80%)(1)

  • Inflammatory abnormality of the skinHP:0011123

Frequent (79-30%)(8)

  • Chronic hepatitisHP:0200123
  • DiarrheaHP:0002014
  • Elevated circulating hepatic transaminase concentrationHP:0002910
  • Maculopapular exanthemaHP:0040186
  • Oral ulcerHP:0000155
  • Recurrent infectionsHP:0002719
  • Skin erosionHP:0200041
  • StomatitisHP:0010280

Occasional (29-5%)(25)

  • Abdominal painHP:0002027
  • Acute hepatitisHP:0200119
  • ArthritisHP:0001369
  • Cutaneous sclerotic plaqueHP:0031359
  • Elevated circulating alkaline phosphatase concentrationHP:0003155
  • FasciitisHP:0100537
  • Gastrointestinal inflammationHP:0004386
  • HemophagocytosisHP:0012156
  • HepatosplenomegalyHP:0001433
  • HyperbilirubinemiaHP:0002904
  • Inflammatory abnormality of the eyeHP:0100533
  • IrritabilityHP:0000737
  • JaundiceHP:0000952
  • Lichenoid skin lesionHP:0031452
  • Limited elbow movementHP:0002996
  • Limited shoulder movementHP:0006467
  • MyositisHP:0100614
  • NauseaHP:0002018
  • PneumoniaHP:0002090
  • Pulmonary infiltratesHP:0002113
  • Recurrent gastroenteritisHP:0031123
  • Scaling skinHP:0040189
  • Skeletal muscle atrophyHP:0003202
  • TachycardiaHP:0001649
  • VomitingHP:0002013

Very rare (<4-1%)(7)

  • Decreased lacrimationHP:0000633
  • Dupuytren contractureHP:0005679
  • Failure to thriveHP:0001508
  • LipodystrophyHP:0009125
  • LymphadenopathyHP:0002716
  • Stiff interphalangeal jointsHP:0005198
  • TrismusHP:0000211