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Congenital syphilis

ORPHA:499009 · Disease · Disorder

HPO 表現型（共 46 項）

Frequent (79-30%)(11)

  • Extramedullary hematopoiesisHP:0001978
  • HepatosplenomegalyHP:0001433
  • Hydrops fetalisHP:0001789
  • Large placentaHP:0006267
  • Maculopapular exanthemaHP:0040186
  • OsteochondrosisHP:0040188
  • PeriostitisHP:0040165
  • PetechiaeHP:0000967
  • Premature birthHP:0001622
  • PurpuraHP:0000979
  • ThrombocytopeniaHP:0001873

Occasional (29-5%)(27)

  • AnemiaHP:0001903
  • CataractHP:0000518
  • ChorioretinitisHP:0012424
  • CSF pleocytosisHP:0012229
  • DiarrheaHP:0002014
  • Frontal bossingHP:0002007
  • GlaucomaHP:0000501
  • Hearing impairmentHP:0000365
  • High palateHP:0000218
  • Hyperplasia of the maxillaHP:0430028
  • Intrauterine growth retardationHP:0001511
  • KeratitisHP:0000491
  • LymphadenopathyHP:0002716
  • MalabsorptionHP:0002024
  • Mulberry molarHP:0011092
  • MyocarditisHP:0012819
  • Nephrotic syndromeHP:0000100
  • Neurodevelopmental delayHP:0012758
  • Notched primary central incisorHP:0012413
  • Palmoplantar scaling skinHP:0025524
  • PancreatitisHP:0001733
  • PneumoniaHP:0002090
  • Prolonged neonatal jaundiceHP:0006579
  • RhinitisHP:0012384
  • Semilunar toothHP:0033782
  • SynovitisHP:0100769
  • UveitisHP:0000554

Very rare (<4-1%)(8)

  • Concave nasal ridgeHP:0011120
  • Cranial nerve paralysisHP:0006824
  • HydrocephalusHP:0000238
  • HypoglycemiaHP:0001943
  • MeningitisHP:0001287
  • Optic atrophyHP:0000648
  • SeizureHP:0001250
  • Tibial bowingHP:0002982