← 返回搜尋

Systemic lupus erythematosus

ORPHA:536 · Disease · Disorder

HPO 表現型（共 44 項）

Very frequent (99-80%)(7)

  • AnorexiaHP:0002039
  • Antinuclear antibody positivityHP:0003493
  • FatigueHP:0012378
  • FeverHP:0001945
  • MalaiseHP:0033834
  • ProteinuriaHP:0000093
  • Weight lossHP:0001824

Frequent (79-30%)(16)

  • AlopeciaHP:0001596
  • Anti-complement component C1q antibody positivityHP:0034077
  • Anti-ribosome Po antibody positivityHP:0034076
  • Anti-titin antibody positivityHP:5000038
  • Antineutrophil antibody positivityHP:0003453
  • ArthritisHP:0001369
  • Decreased circulating complement C3 concentrationHP:0005421
  • Decreased circulating complement C4 concentrationHP:0045042
  • Decreased total leukocyte countHP:0001882
  • HematuriaHP:0000790
  • HypertensionHP:0000822
  • Lupus nephritisHP:0033726
  • Malar rashHP:0025300
  • Polyarticular arthritisHP:0005764
  • PyuriaHP:0012085
  • Raynaud phenomenonHP:0030880

Occasional (29-5%)(19)

  • Abnormal pigmentation of the oral mucosaHP:0100669
  • Abnormality of salivationHP:0100755
  • Anti-dsDNA antibody positivityHP:0020151
  • Anti-La/SS-B antibody positivityHP:0032235
  • Anti-nucleoporin 62 antibody positivityHP:0033556
  • Anti-phosphatidic acid antibody positivityHP:0034096
  • Anti-Ro52/TRIM21 antibody positivityHP:0034093
  • Anti-Sm antibody positivityHP:0033040
  • Anti-U1 ribonucleoprotein antibody positivityHP:0033028
  • CheilitisHP:0100825
  • Cutaneous photosensitivityHP:0000992
  • DepressionHP:0000716
  • Discoid lupus rashHP:0007417
  • Hemolytic anemiaHP:0001878
  • LymphadenopathyHP:0002716
  • Oral ulcerHP:0000155
  • SeizureHP:0001250
  • SerositisHP:0045073
  • ThrombocytopeniaHP:0001873

Very rare (<4-1%)(2)

  • ChoreaHP:0002072
  • RetinopathyHP:0000488