← 返回搜尋

Methotrexate toxicity

ORPHA:565782 · Disease · Disorder

HPO 表現型（共 22 項）

Frequent (79-30%)(4)

  • Abdominal painHP:0002027
  • Decreased liver functionHP:0001410
  • Elevated circulating hepatic transaminase concentrationHP:0002910
  • VomitingHP:0002013

Occasional (29-5%)(17)

  • AlopeciaHP:0001596
  • CirrhosisHP:0001394
  • ConfusionHP:0001289
  • Decreased total leukocyte countHP:0001882
  • DrowsinessHP:0002329
  • FatigueHP:0012378
  • FeverHP:0001945
  • Gastrointestinal hemorrhageHP:0002239
  • HeadacheHP:0002315
  • Interstitial pneumonitisHP:0006515
  • Megaloblastic anemiaHP:0001889
  • NauseaHP:0002018
  • Oral ulcerHP:0000155
  • PancreatitisHP:0001733
  • Renal insufficiencyHP:0000083
  • SeizureHP:0001250
  • VertigoHP:0002321

Very rare (<4-1%)(1)

  • ConjunctivitisHP:0000509