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Microscopic polyangiitis

ORPHA:727 · Disease · Disorder

HPO 表現型（共 55 項）

Very frequent (99-80%)(13)

  • AutoimmunityHP:0002960
  • Crescentic glomerulonephritisHP:0008653
  • ErythemaHP:0010783
  • FeverHP:0001945
  • GlomerulonephritisHP:0000099
  • GlomerulopathyHP:0100820
  • HematuriaHP:0000790
  • HemoptysisHP:0002105
  • Increased inflammatory responseHP:0012649
  • OliguriaHP:0100520
  • Renal insufficiencyHP:0000083
  • Skin rashHP:0000988
  • VasculitisHP:0002633

Frequent (79-30%)(22)

  • Abdominal painHP:0002027
  • Abnormal urine cytologyHP:0012614
  • AnemiaHP:0001903
  • Anti-myeloperoxidase antibody positivityHP:0033559
  • Anti-neutrophil elastase antibody positivityHP:0034104
  • Anti-proteinase 3 antibody positivityHP:0033557
  • ArthralgiaHP:0002829
  • Cytoplasmic antineutrophil antibody positivityHP:0032230
  • DiarrheaHP:0002014
  • Elevated erythrocyte sedimentation rateHP:0003565
  • FatigueHP:0012378
  • Gastrointestinal hemorrhageHP:0002239
  • Gastrointestinal infarctionsHP:0005244
  • Livedo reticularisHP:0033505
  • Multiple mononeuropathyHP:0032018
  • MyalgiaHP:0003326
  • Nausea and vomitingHP:0002017
  • PeritonitisHP:0002586
  • Poor appetiteHP:0004396
  • Skin ulcerHP:0200042
  • Subcutaneous hemorrhageHP:0001933
  • Venous thrombosisHP:0004936

Occasional (29-5%)(20)

  • Abnormal retinal vascular morphologyHP:0008046
  • ArrhythmiaHP:0011675
  • ArthritisHP:0001369
  • Chest painHP:0100749
  • Congestive heart failureHP:0001635
  • Cutis marmorataHP:0000965
  • Diffuse alveolar hemorrhageHP:0025420
  • EpiscleritisHP:0100534
  • EpistaxisHP:0000421
  • GangreneHP:0100758
  • Palpable purpuraHP:0031363
  • PancreatitisHP:0001733
  • ParesthesiaHP:0003401
  • PericarditisHP:0001701
  • Peripheral neuropathyHP:0009830
  • Retinal vasculitisHP:0025188
  • SinusitisHP:0000246
  • Subcutaneous noduleHP:0001482
  • UveitisHP:0000554
  • Weight lossHP:0001824