← 返回搜尋

Polymyositis

ORPHA:732 · Disease · Disorder

HPO 表現型（共 60 項）

Very frequent (99-80%)(9)

  • Abnormal muscle fiber morphologyHP:0004303
  • ArthralgiaHP:0002829
  • AutoimmunityHP:0002960
  • CoughHP:0012735
  • Elevated circulating aldolase concentrationHP:0012544
  • Elevated circulating creatine kinase activityHP:0003236
  • EMG abnormalityHP:0003457
  • HypotoniaHP:0001252
  • Proximal muscle weaknessHP:0003701

Frequent (79-30%)(21)

  • Abnormal pulmonary interstitial morphologyHP:0006530
  • AnorexiaHP:0002039
  • Anti-alanyl-tRNA synthetase antibody positivityHP:0034145
  • Anti-aminoacyl-tRNA synthetase antibody positivityHP:0034147
  • Anti-asparaginyl-tRNA synthetase antibody positivityHP:0034151
  • Anti-glycyl tRNA-synthetase antibody positivityHP:0034146
  • Anti-histidyl tRNA synthetase antibody positivityHP:0034152
  • Anti-isoleucyl tRNA-synthetase antibody positivityHP:0034148
  • Anti-phenylalanyl tRNA synthetase antibody positivityHP:0034149
  • Anti-signal recognition particle antibody positivityHP:0033713
  • Anti-threonyl-tRNA synthetase antibody positivityHP:0034143
  • Anti-tyrosyl-tRNA synthetase antibody positivityHP:0034150
  • Antinuclear antibody positivityHP:0003493
  • ArthritisHP:0001369
  • ConstipationHP:0002019
  • Exertional dyspneaHP:0002875
  • FatigueHP:0012378
  • FeverHP:0001945
  • MyalgiaHP:0003326
  • Respiratory insufficiencyHP:0002093
  • Weight lossHP:0001824

Occasional (29-5%)(30)

  • Abdominal painHP:0002027
  • Abnormal atrioventricular conductionHP:0005150
  • Abnormal mitral valve morphologyHP:0001633
  • Abnormal renal tubule morphologyHP:0000091
  • Abnormality of the voiceHP:0001608
  • ArrhythmiaHP:0011675
  • CamptocormiaHP:0100595
  • Chest tightnessHP:0031352
  • ChondrocalcinosisHP:0000934
  • Congestive heart failureHP:0001635
  • Dilated cardiomyopathyHP:0001644
  • Diminished deep tendon reflexHP:0001315
  • DysphoniaHP:0001618
  • Elevated erythrocyte sedimentation rateHP:0003565
  • Gait disturbanceHP:0001288
  • Gastroesophageal refluxHP:0002020
  • Gastrointestinal hemorrhageHP:0002239
  • HepatomegalyHP:0002240
  • Hypernasal speechHP:0001611
  • Hypertrophic cardiomyopathyHP:0001639
  • Increased total lymphocyte countHP:0100827
  • Myocardial infarctionHP:0001658
  • Neuromuscular dysphagiaHP:0002068
  • PericarditisHP:0001701
  • Pulmonary fibrosisHP:0002206
  • Raynaud phenomenonHP:0030880
  • Skin rashHP:0000988
  • ThrombocytosisHP:0001894
  • VasculitisHP:0002633
  • Venous thrombosisHP:0004936