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Rheumatoid factor-positive polyarticular juvenile idiopathic arthritis

ORPHA:85435 · Disease · Disorder

HPO 表現型（共 19 項）

Very frequent (99-80%)(4)

  • ArthralgiaHP:0002829
  • ArthritisHP:0001369
  • Polyarticular arthritisHP:0005764
  • Rheumatoid factor positiveHP:0002923

Frequent (79-30%)(11)

  • Abnormal circulating interleukin concentrationHP:0011117
  • Abnormal epiphysis morphologyHP:0005930
  • Abnormal limb bone morphologyHP:0002813
  • Elevated circulating C-reactive protein concentrationHP:0011227
  • Elevated erythrocyte sedimentation rateHP:0003565
  • Interphalangeal joint erosionsHP:0006252
  • Joint swellingHP:0001386
  • Limitation of joint mobilityHP:0001376
  • Progressive joint destructionHP:0005187
  • Symmetric polyarthritisHP:0040311
  • SynovitisHP:0100769

Occasional (29-5%)(4)

  • Asymmetric growthHP:0100555
  • OsteopeniaHP:0000938
  • Premature epimetaphyseal fusionHP:0010588
  • Reduced bone mineral densityHP:0004349