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Acute panmyelosis with myelofibrosis

ORPHA:86843 · Disease · Disorder

HPO 表現型（共 15 項）

Very frequent (99-80%)(2)

  • MyelofibrosisHP:0011974
  • PancytopeniaHP:0001876

Frequent (79-30%)(5)

  • Abnormal megakaryocyte morphologyHP:0012143
  • Abnormality of bone marrow stromal cellsHP:0012129
  • Bone marrow hypercellularityHP:0031020
  • FatigueHP:0012378
  • Muscle weaknessHP:0001324

Occasional (29-5%)(7)

  • Acute myeloid leukemiaHP:0004808
  • Acute myelomonocytic leukemiaHP:0004820
  • Bone marrow hypocellularityHP:0005528
  • Increased micromegakaryocyte countHP:0031386
  • Increased total lymphocyte countHP:0100827
  • Low back painHP:0003419
  • Megakaryocyte nucleus hypolobulationHP:0031385

Very rare (<4-1%)(1)

  • SplenomegalyHP:0001744