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Functioning gonadotropic adenoma

ORPHA:91348 · Disease · Disorder

HPO 表現型（共 34 項）

Obligate (100%)(1)

  • Pituitary gonadotropic cell adenomaHP:0011759

Frequent (79-30%)(10)

  • Abnormal prolactin levelHP:0040086
  • Abnormality of the menstrual cycleHP:0000140
  • Anterior hypopituitarismHP:0000830
  • Decreased female libidoHP:0030018
  • FatigueHP:0012378
  • ImpotenceHP:0000802
  • Increased serum testosterone levelHP:0030088
  • InfertilityHP:0000789
  • Visual field defectHP:0001123
  • Visual impairmentHP:0000505

Occasional (29-5%)(23)

  • Abnormality of secondary sexual hairHP:0009888
  • Adrenocorticotropic hormone deficiencyHP:0011748
  • AmenorrheaHP:0000141
  • AscitesHP:0001541
  • Central diabetes insipidusHP:0000863
  • Decreased response to growth hormone stimulation testHP:0000824
  • Deep venous thrombosisHP:0002625
  • Delayed pubertyHP:0000823
  • Delayed skeletal maturationHP:0002750
  • Enlarged polycystic ovariesHP:0008675
  • GalactorrheaHP:0100829
  • HeadacheHP:0002315
  • HydrocephalusHP:0000238
  • Increased circulating gonadotropin levelHP:0000837
  • Isosexual precocious pubertyHP:0008236
  • Macroorchidism, postpubertalHP:0002050
  • Oculomotor nerve palsyHP:0012246
  • OligozoospermiaHP:0000798
  • OsteopeniaHP:0000938
  • OsteoporosisHP:0000939
  • Ovarian cystHP:0000138
  • PanhypopituitarismHP:0000871
  • Pituitary hypothyroidismHP:0008245