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Panhypophysitis

ORPHA:95513 · Disease · Disorder

HPO 表現型（共 35 項）

Very frequent (99-80%)(3)

  • Abnormal posterior pituitary morphogenesisHP:0011751
  • Central diabetes insipidusHP:0000863
  • PanhypopituitarismHP:0000871

Frequent (79-30%)(24)

  • Abnormal size of pituitary glandHP:0012504
  • Abnormal thalamic MRI signal intensityHP:0012696
  • Adrenocorticotropic hormone deficiencyHP:0011748
  • Adrenocorticotropin deficient adrenal insufficiencyHP:0011735
  • AmenorrheaHP:0000141
  • Blurred visionHP:0000622
  • Decreased circulating cortisol levelHP:0008163
  • Decreased female libidoHP:0030018
  • Decreased male libidoHP:0040306
  • Decreased serum estradiolHP:0008214
  • Decreased serum testosterone concentrationHP:0040171
  • Gonadotropin deficiencyHP:0008213
  • HeadacheHP:0002315
  • HyposthenuriaHP:0003158
  • ImpotenceHP:0000802
  • Increased circulating prolactin concentrationHP:0000870
  • NauseaHP:0002018
  • Normochromic anemiaHP:0001895
  • Orthostatic hypotensionHP:0001278
  • PallorHP:0000980
  • Pituitary hypothyroidismHP:0008245
  • PolydipsiaHP:0001959
  • Progressive visual field defectsHP:0007987
  • Secondary growth hormone deficiencyHP:0008240

Occasional (29-5%)(8)

  • Antinuclear antibody positivityHP:0003493
  • Chronic lymphocytic meningitisHP:0007041
  • DiplopiaHP:0000651
  • Hashimoto thyroiditisHP:0000872
  • HyponatremiaHP:0002902
  • Poor appetiteHP:0004396
  • Reduced circulating prolactin concentrationHP:0008202
  • Sensorineural hearing impairmentHP:0000407