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Atrial septal defect, ostium secundum type

ORPHA:99103 · Clinical subtype · Subtype of disorder

HPO 表現型（共 35 項）

Very frequent (99-80%)(1)

  • Left-to-right shuntHP:0012382

Frequent (79-30%)(6)

  • Exercise intoleranceHP:0003546
  • Exertional dyspneaHP:0002875
  • FatigueHP:0012378
  • PalpitationsHP:0001962
  • Right atrial enlargementHP:0030718
  • Systolic heart murmurHP:0031664

Occasional (29-5%)(19)

  • Abnormal left ventricular functionHP:0005162
  • Abnormal mitral valve morphologyHP:0001633
  • ArrhythmiaHP:0011675
  • Atrial fibrillationHP:0005110
  • Atrial flutterHP:0004749
  • Breathing dysregulationHP:0005957
  • Bundle branch blockHP:0011710
  • Congestive heart failureHP:0001635
  • DyspneaHP:0002094
  • First degree atrioventricular blockHP:0011705
  • Mitral regurgitationHP:0001653
  • OrthopneaHP:0012764
  • Pedal edemaHP:0010741
  • Pulmonary arterial hypertensionHP:0002092
  • Right ventricular dilatationHP:0005133
  • ST segment depressionHP:0012250
  • Supraventricular arrhythmiaHP:0005115
  • Supraventricular tachycardiaHP:0004755
  • Tricuspid regurgitationHP:0005180

Very rare (<4-1%)(9)

  • Airway obstructionHP:0006536
  • CyanosisHP:0000961
  • Increased pulmonary vascular resistanceHP:0005317
  • PneumoniaHP:0002090
  • Recurrent bacterial infectionsHP:0002718
  • Right ventricular failureHP:0001708
  • StrokeHP:0001297
  • SyncopeHP:0001279
  • Transient ischemic attackHP:0002326