← 返回搜尋

Pituitary gigantism

ORPHA:99725 · Disease · Disorder

HPO 表現型（共 20 項）

Very frequent (99-80%)(16)

  • Accelerated skeletal maturationHP:0005616
  • Coarse facial featuresHP:0000280
  • Elevated circulating growth hormone concentrationHP:0000845
  • Frontal bossingHP:0002007
  • HyperhidrosisHP:0000975
  • Hypertrophic cardiomyopathyHP:0001639
  • Increased circulating insulin-like growth factor 1 concentrationHP:0030269
  • Large handsHP:0001176
  • Left ventricular hypertrophyHP:0001712
  • Long footHP:0001833
  • Mandibular prognathiaHP:0000303
  • Pituitary growth hormone cell adenomaHP:0011760
  • Premature pubarcheHP:0012411
  • Proportionate tall statureHP:0011407
  • Tall statureHP:0000098
  • Type II diabetes mellitusHP:0005978

Frequent (79-30%)(3)

  • AmenorrheaHP:0000141
  • Increased circulating prolactin concentrationHP:0000870
  • Pituitary prolactin cell adenomaHP:0006767

Occasional (29-5%)(1)

  • GalactorrheaHP:0100829