← 返回搜尋

Marburg hemorrhagic fever

ORPHA:99826 · Disease · Disorder

HPO 表現型（共 74 項）

Very frequent (99-80%)(5)

  • Capillary leakHP:0030005
  • Decreased total leukocyte countHP:0001882
  • Decreased total lymphocyte countHP:0001888
  • Increased circulating immunoglobulin concentrationHP:0010702
  • ViremiaHP:0020071

Frequent (79-30%)(16)

  • Abdominal painHP:0002027
  • Abnormal bleedingHP:0001892
  • Abnormal lymphocyte morphologyHP:0004332
  • Abnormal number of granulocyte precursorsHP:0012137
  • AnorexiaHP:0002039
  • ChillsHP:0025143
  • Conjunctival hyperemiaHP:0030953
  • DiarrheaHP:0002014
  • FeverHP:0001945
  • HeadacheHP:0002315
  • MyalgiaHP:0003326
  • Neutrophilia in presence of infectionHP:0410257
  • OdynophagiaHP:0032043
  • ReticulocytosisHP:0001923
  • Severe infectionHP:0032169
  • VomitingHP:0002013

Occasional (29-5%)(40)

  • Abnormality of the coagulation cascadeHP:0003256
  • Aggressive behaviorHP:0000718
  • ArthralgiaHP:0002829
  • Atypical absence status epilepticusHP:0011151
  • Back painHP:0003418
  • Bloody diarrheaHP:0025085
  • BradycardiaHP:0001662
  • Bruising susceptibilityHP:0000978
  • ComaHP:0001259
  • ConfusionHP:0001289
  • DehydrationHP:0001944
  • DrowsinessHP:0002329
  • DysesthesiaHP:0012534
  • Elevated circulating creatine kinase activityHP:0003236
  • Elevated circulating creatinine concentrationHP:0003259
  • Elevated circulating hepatic transaminase concentrationHP:0002910
  • Excessive bleeding after a venipunctureHP:0030139
  • HyperamylasemiaHP:0410288
  • HypoalbuminemiaHP:0003073
  • HypoglycemiaHP:0001943
  • HypokalemiaHP:0002900
  • HypotensionHP:0002615
  • HypothermiaHP:0002045
  • Internal hemorrhageHP:0011029
  • Lactic acidosisHP:0003128
  • LethargyHP:0001254
  • LymphadenopathyHP:0002716
  • Maculopapular exanthemaHP:0040186
  • NauseaHP:0002018
  • Nonproductive coughHP:0031246
  • PetechiaeHP:0000967
  • Prolonged partial thromboplastin timeHP:0003645
  • Prolonged prothrombin timeHP:0008151
  • Renal insufficiencyHP:0000083
  • SeizureHP:0001250
  • ShockHP:0031273
  • Skin rashHP:0000988
  • Subconjunctival hemorrhageHP:0011896
  • TachycardiaHP:0001649
  • ThrombocytopeniaHP:0001873

Very rare (<4-1%)(13)

  • Abnormality of acid-base homeostasisHP:0004360
  • Abnormality of the gastrointestinal tractHP:0011024
  • ArthritisHP:0001369
  • Disseminated intravascular coagulationHP:0005521
  • Hepatic encephalopathyHP:0002480
  • HyperammonemiaHP:0001987
  • HypovolemiaHP:0011106
  • JaundiceHP:0000952
  • OrchitisHP:0100796
  • PancreatitisHP:0001733
  • PericarditisHP:0001701
  • PsychosisHP:0000709
  • UveitisHP:0000554