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Crimean-Congo hemorrhagic fever

ORPHA:99827 · Disease · Disorder

HPO 表現型（共 78 項）

Very frequent (99-80%)(4)

  • Capillary leakHP:0030005
  • FeverHP:0001945
  • Increased circulating IgM concentrationHP:0003496
  • ThrombocytopeniaHP:0001873

Frequent (79-30%)(17)

  • Abdominal painHP:0002027
  • AnorexiaHP:0002039
  • Decreased prothrombin timeHP:0032198
  • DiarrheaHP:0002014
  • Elevated circulating creatine kinase activityHP:0003236
  • EpistaxisHP:0000421
  • HeadacheHP:0002315
  • HepatomegalyHP:0002240
  • Increased circulating IgG concentrationHP:0003237
  • Increased circulating lactate dehydrogenase concentrationHP:0025435
  • MyalgiaHP:0003326
  • Nausea and vomitingHP:0002017
  • Neck painHP:0030833
  • Ocular painHP:0200026
  • Prolonged partial thromboplastin timeHP:0003645
  • Stiff neckHP:0025258
  • ViremiaHP:0020071

Occasional (29-5%)(30)

  • Abnormality of the nervous systemHP:0000707
  • AgitationHP:0000713
  • BradycardiaHP:0001662
  • ChillsHP:0025143
  • ComaHP:0001259
  • ConfusionHP:0001289
  • ConjunctivitisHP:0000509
  • Decreased total leukocyte countHP:0001882
  • EcchymosisHP:0031364
  • Emotional labilityHP:0000712
  • Excessive daytime somnolenceHP:0001262
  • FasciculationsHP:0002380
  • Gingival bleedingHP:0000225
  • HematemesisHP:0002248
  • HematuriaHP:0000790
  • HemoptysisHP:0002105
  • Hepatic failureHP:0001399
  • HyperhidrosisHP:0000975
  • HypertensionHP:0000822
  • HypotensionHP:0002615
  • Increased total leukocyte countHP:0001974
  • JaundiceHP:0000952
  • LymphadenopathyHP:0002716
  • MelenaHP:0002249
  • PhotophobiaHP:0000613
  • PurpuraHP:0000979
  • Recurrent singultusHP:0100247
  • SplenomegalyHP:0001744
  • TachycardiaHP:0001649
  • VertigoHP:0002321

Very rare (<4-1%)(27)

  • Abnormal left ventricular functionHP:0005162
  • Acute pancreatitisHP:0001735
  • Adrenal insufficiencyHP:0000846
  • ArthralgiaHP:0002829
  • AscitesHP:0001541
  • Bundle branch blockHP:0011710
  • CholecystitisHP:0001082
  • Diffuse alveolar hemorrhageHP:0025420
  • EpididymitisHP:0000031
  • Erythema nodosumHP:0012219
  • HemoperitoneumHP:0011854
  • HemothoraxHP:0012151
  • Inappropriate antidiuretic hormone secretionHP:0031218
  • Increased total neutrophil countHP:0011897
  • Internal hemorrhageHP:0011029
  • Morbilliform rashHP:0012282
  • MyocarditisHP:0012819
  • OrchitisHP:0100796
  • PancytopeniaHP:0001876
  • ParotitisHP:0011850
  • Pericardial effusionHP:0001698
  • ProteinuriaHP:0000093
  • Pulmonary arterial hypertensionHP:0002092
  • Retinal hemorrhageHP:0000573
  • Spontaneous hematomasHP:0007420
  • Subconjunctival hemorrhageHP:0011896
  • Subdural hemorrhageHP:0100309